LEMIRE databases

Database Metadata analyses and bacterial regulatory systems databases To carry out our work, bioinformatics tools are used/developed at LEMiRE for metadata analysis, in silico studies, genome mining and creation of regulator databases. Databases : Rapid changes in the physico-chemical conditions of the environment of bacteria require an adjustment of their physiology that may involve a […]

LEMIRE research themes and projects

Research topics Plants have co-evolved with their microbiota for more than 300 million years. The whole genome of this microbiota (microbiome) is an extension of the host plant genome (holobiont). The interactions between the host and its microbiota rely on sophisticated ways to communicate and coexist. Complex, interconnected networks of signals and metabolites modulate the […]

LEMIRE

Pseudomonas brassicacearum – Expression de l’ARN non codant rsmW Previous Next Team Microbial Ecology of the Rhizosphere Research on soil-plant-microbiota interactions Adaptive strategies and exploration of phytobeneficial bacterial genomes for a sustainable agriculture Research at LEMiRE is devoted to the study of the “soil-plant-microbiota interactions”, with a particular focus on the potential role of the […]

IPM Research Themes

Research topics Response to uranium and radionuclides of environmental bacteria Soil bacteria interact with metals and radionuclides (RN) and can modify their chemical speciation, thus modulating their mobility and bioavailability. Radionuclides are chemo- and radio-toxic elements that can in turn induce cellular stress and against which certain species exhibit a high tolerance capacity. At the […]

IPM equipment

Our equipments “Micro TOF-Q” mass spectrometer (Bruker) The Metal Protein Interactions team has a “micro TOF-Q” mass spectrometer (Bruker) with hybrid geometry type Q-TOF (quadripole – Time Of Flight) equipped with an electrospray source (ESI). The ESI Q-TOF mass spectrometer enables high-precision analyses to be carried out on proteins or protein complexes of high molecular […]

IPM team and skills

Our Protein-Metal Interactions team The current team members Team Leader Catherine BERTHOMIEU Team ManagerResearch DirectorCEA Virginie CHAPON Deputy managerResearcherCEA Permanent positions Véronique MALARD ResearcherCEA Sandrine SAUGE-MERLE ResearcherCEA Nicolas BREMOND EngineerCEA David LEMAIRE Research engineerCEA Anne CHEVALIER TechnicianCEA Laurie PIETTE-BARRERE TechnicianCEA Fixed-term contracts and internships Loïc ALEMAN PhD student Loïc DARONNAT PhD student Nicolas JANS-ROBINSON PhD […]

IPM

Team Interactions Protein-Metal Metals play a fundamental role in biology, in particular because they are essential to the functioning of many proteins. But they can also be toxic because of their intrinsic properties or for some of them like actinides, 90Sr, or 60Co because they are radioactive. We seek to decipher the mechanisms of these […]

EBMP research topics and projects

Research axes 1. From nutrient sensing to nutrient homeostasis and biomass growth Photosynthetic growth relies on a balanced supply of solar energy, CO2 and nutrients (nitrogen, phosphate, iron…). Faced with a fluctuating environment (nutrient availability, temperature increase, water shortage, fluctuating CO2 levels…), cells must constantly adjust their metabolism to ensure their survival. In order to […]

EBMP publications

EBM Publications EBM Patents 2016 Beisson F, Sorigué D, Légeret B, Cuiné S, Blangy S, Peltier G (2016)  “New fatty acid decarboxylase and its uses.” European Patent Application n°16 305583.3. 2014 Schulz-Raffelt M, Chochois V, Li-Beisson Y, Peltier G (2014) Green microalgae lacking a functional DYRK-1 gene, for use for production of feedstock (EP14305673.7). 2008 […]